Hi,
I have relationship (to custom post type) field on user settings page. When I focus on it, it will disable “Update User”-button and it won’t be enabled until I refresh the page. I don’t have any custom filters on ACF fields.
Wordpress 4.3.1
ACF Pro 5.3.1
Every other plugin is disabled.
If I manually remove disable-attribute from button and click it the button will work and data is saved correctly.
I’ve tried it and it seems to be working for me.
Do you have any other plugins installed? Check for a JavaScript error, that could cause the issue. Try disabling other plugins, maybe that will give you a clue where the error is.