Thanks for your reply @elliot
It is happening in the backend, the file upload field is within a repeater, which is part of a flexible content field.
I have not got any WordPress upload issues with the other forms like the media upload button on a page.
Very strange. If the error persists, I’ll get the error from my PHP log and report it here.
I normally have no issues uploading on this server with ACF (I use it all the time). The only thing new that I’ve done is update to the newest version.