Why would you want to exclude the field label and instructions? How will anyone know what the field is for?
But the answer is, yes, you probably can by using an acf/prepare_field filter and setting $field['label'] and $field['instructions'] to an empty string. https://www.advancedcustomfields.com/resources/acfprepare_field/.
Or you can add some custom CSS to the front of your site to hide them.
