@mortenskyt
I’m liking your use of classes for fields, which got me thinking about an abstracted static class for performing similar look-ups & related tasks.
Using the function posted above, however, you could eliminate the required cut-and-paste:
update_field( get_acf_field_key('registration_number'), $registration_number, $postID);
@elliot – any interest in including something like this in core? Any suggestions?