It depends on the fields. For simple text fields it doesn’t matter much. This includes anything that is stored as a text value. But for fields that are stored as serialized arrays or for things like image fields that store image ID this can be a problem.
You should use update_field() in ACF using the field_keys for the fields. Either that or add the ACF meta values manually. I’d go with using update_field() https://www.advancedcustomfields.com/resources/update_field/
