That depends on what version of ACF you’re using.
ACF5 (Pro) has a location rule for the user add/edit page, this would be my choice.
For ACF4, you may be able to create a custom location rule, but, to be honest, I’m not entirely sure it’s possible at all with this version. You might need to add a custom post type for holding user information and put a user field on that post type that relates the post to the user and then to get the values you’d need to search the posts for the post for that user. You’d also need to set the post type up so that the user can edit it. There’s a lot of work here, ACF5 Pro would be well worth the investment for just the ability to add fields to the user profile page.
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