This tutorial goes over everything you need to query relationship fields http://www.advancedcustomfields.com/resources/querying-relationship-fields/
Basically, for what you want you need to use “LIKE” and the double quotes around the value are important.
$args = array(
'numberposts' => -1,
'post_type' => 'post',
'meta_query' => array(
array(
'key' => 'relation_user',
'value' => '"1"',
'compare' => 'LIKE',
)
)
);