What you are looking for is that you need to create query variables in the URL and then filter the posts by these query variables. While you’re using ACF to create and display the custom fields you’re problem really isn’t with ACF.
You are either going to need a form that submits the filter values or you will need to generate URL that include query strings with the the values. Then you need to get the values from $_GET and generate the QP_Query using those values.
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