have the filter run after ACF (priority 20)
Then you get use get_field to get the radio field and update_field if you want to clear it but leave the DB entries.
If you want to completely delete the db entry you’ll need to use delete_post_meta() WP function and you will need to delete 2 values.
'your_field_name'
AND
'_your_field_name'
If you are doing this for repeater fields or other nested fields you should look at the database to see how ACF names these types of fields.