@hube2 No, It you can make external src image url to featured image by post_thumbnail_html
.
But i don’t know how can i do it with ACF custom fields value.
Here is the few links:
https://wordpress.stackexchange.com/a/158568/210558
https://wordpress.stackexchange.com/a/342159/210558
If you know how can i get image src url value from custom fields and set it to featured image then plz tell me?