Any individual script or style sheet can be removed using https://developer.wordpress.org/reference/functions/wp_dequeue_script/ and https://developer.wordpress.org/reference/functions/wp_dequeue_style/. The trick is finding the right handle and the right time to remove them. For acf I would try the acf/admin_enqueue_scripts hook with a high priority. However, you may see unintended side effects since a lot of ACF depends on these 3rd party scripts and styles.
