ACF has changed a lot since I’ve tried this. I think it is possible as I believe that ACF is showing options pages in a way that uses some of the standard WP hooks. Unfortunately I can’t point you to any code… I did leave myself a note about it though here https://github.com/Hube2/acf-options-page-adder/issues/51… and it appears I explained it to some extent here https://support.advancedcustomfields.com/forums/topic/hooks-on-options-pages/#post-62424
